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Cybin (TSE:CYBN)
NEO-L:CYBN

Cybin (CYBN) AI Stock Analysis

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TSE:CYBN

Cybin

(NEO-L:CYBN)

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Underperform 37 (OpenAI - 4o)
Rating:37Underperform
Price Target:
Cybin's stock score is significantly impacted by its lack of revenue and continuous financial losses, resulting in a low valuation score. While technical indicators are neutral, positive corporate events indicate potential for future growth. However, current financial challenges remain the dominant concern.

Cybin (CYBN) vs. iShares MSCI Canada ETF (EWC)

Cybin Business Overview & Revenue Model

Company DescriptionCybin Inc., a biopharmaceutical company, focuses on developing psychedelic-based therapeutics. The company's development pipeline includes CYB003, a deuterated psilocybin analog to treat major depressive and alcohol use disorders; CYB004, a deuterated dimethyltryptamine for treating anxiety disorders; and CYB005, a phenethylamine derivative to treat neuroinflammation. It has also developed EMBARK, a psychedelic-assisted psychotherapy. The company is headquartered in Toronto, Canada.
How the Company Makes MoneyCybin makes money through the development and commercialization of psychedelic-based therapeutics. The company's revenue streams primarily include partnerships and collaborations with research institutions and pharmaceutical companies, conducting clinical trials, and potentially licensing its proprietary drug formulations and delivery technologies. As Cybin progresses through clinical trials and moves towards regulatory approval, it may also generate income through milestone payments and eventual sales of approved drugs. Strategic partnerships and collaborations play a significant role in supporting Cybin's research initiatives, contributing to funding and resources for its development programs.

Cybin Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Feb 17, 2026
Earnings Call Sentiment Neutral
The earnings call reflects a company making significant progress in advancing its clinical programs and strengthening its financial position, despite facing challenges such as leadership transition and increased expenses. The overall sentiment is balanced, with solid achievements in clinical and operational fronts but offset by financial and leadership concerns.
Q2-2026 Updates
Positive Updates
Advancement in Clinical Programs
CYB003 Phase III program for major depressive disorder and CYB004 Phase II program for generalized anxiety disorder are progressing as planned. The CYB004 study completed enrollment and is on track for a top line readout in the first calendar quarter of 2026.
Successful Financing and Strengthened Capital Position
Closed a $175 million financing, providing flexibility to execute plans and retire convertible debentures. Ended the quarter with $83.8 million in cash, cash equivalents, and investments.
Global Study Expansion
EMBRACE Phase III study for CYB003 has been cleared to commence in the United States, U.K., multiple European Union countries, and Australia.
Operational and Commercial Readiness
Partnership with Thermo Fisher for manufacturing and Osmind for point-of-care software to enhance clinic workflow and data management.
Positive Market and Investor Confidence
Participation from prominent institutional healthcare investors in recent financing reflects confidence in Cybin's science and programs.
Negative Updates
Leadership Transition
Doug Drysdale stepped down as CEO, and the company is currently searching for a permanent CEO, which could impact leadership stability.
Increased Operating Expenses
Cash-based operating expenses increased to $28.5 million for the quarter, up from $18.2 million in the same period last year.
Significant Net Loss
Reported a net loss of $33.7 million for the quarter ended September 30, 2025, compared to a net loss of $41.9 million in the same period last year.
Challenges in Site Activation
Competition for resources at clinical trial sites due to the number of ongoing psychedelic trials posed a challenge in site selection and activation.
Company Guidance
In the recent call, Cybin provided several key metrics and updates regarding their ongoing programs and financial status. The company has raised $175 million in recent financing, aiming to advance their lead programs, CYB003 and CYB004, towards significant data readouts. CYB003, a deuterated psilocin analog, is in Phase III for major depressive disorder and has expanded its global footprint, targeting 330 participants across approximately 60 clinical sites. CYB004, targeting generalized anxiety disorder, has completed Phase II enrollment, with top-line data expected in Q1 2026. For the fiscal quarter ending September 30, 2025, Cybin reported cash-based operating expenses of $28.5 million and a net loss of $33.7 million. The company ended the quarter with $83.8 million in cash, cash equivalents, and investments, projecting these funds to support operations into 2027. Cybin emphasizes a disciplined approach to capital deployment, focusing on measurable milestones, global site activations, and manufacturing readiness to ensure successful execution of their clinical and commercial strategies.

Cybin Financial Statement Overview

Summary
Cybin faces financial difficulties with no current revenue and persistent net losses. Despite a strong equity base and cash reserves, the lack of revenue and positive cash flow poses sustainability risks.
Income Statement
15
Very Negative
Cybin has been experiencing significant financial challenges, evident from the absence of revenue in recent periods and substantial net losses. The company reported a negative EBIT and EBITDA, indicating operational inefficiencies and high costs relative to its revenue base. Historically, there was some revenue in 2021, but it has since dropped to zero, highlighting a concerning trend in revenue generation.
Balance Sheet
45
Neutral
The balance sheet shows a strong equity position with zero debt, suggesting a conservative capital structure. However, the lack of revenue is a significant concern. The equity ratio is high, showcasing reliance on equity rather than debt. The company maintains a healthy cash position, but sustained losses could erode this over time.
Cash Flow
20
Very Negative
Cash flow from operations is negative, reflecting ongoing operational cash burn. Although the company has raised substantial financing, the free cash flow remains negative, indicating cash outflows exceed inflows. This trend suggests potential liquidity issues if the cash burn continues without revenue improvement.
BreakdownTTMDec 2025Dec 2025Dec 2024Dec 2023Dec 2022
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-52.59K0.00-424.00K-251.00K-168.00K
EBITDA-147.08M-142.67M-78.58M-47.24M-63.67M
Net Income-122.93M-113.14M-78.08M-47.49M-67.63M
Balance Sheet
Total Assets210.81M258.62M302.02M53.90M92.11M
Cash, Cash Equivalents and Short-Term Investments118.69M135.02M208.99M16.63M64.03M
Total Debt44.50M0.00291.00K0.000.00
Total Liabilities59.05M21.42M10.10M5.66M5.99M
Stockholders Equity151.76M237.20M291.93M48.23M86.12M
Cash Flow
Free Cash Flow-105.59M-103.27M-69.62M-50.74M-19.26M
Operating Cash Flow-103.63M-101.30M-68.91M-47.43M-19.03M
Investing Cash Flow-1.95M-1.97M6.92M-3.31M-1.19M
Financing Cash Flow75.06M20.20M254.51M13.56M35.78M

Cybin Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
42
Neutral
C$5.69M-6.75-32.09%-50.89%-32.33%
37
Underperform
$1.92M-0.02-53.20%33.28%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:CYBN
Cybin
0.14
0.00
0.00%
TSE:HEAL
Restart Life Sciences
0.11
0.03
37.50%
TSE:WAVE
Waverley Pharma
0.02
0.00
0.00%
TSE:MYND
MYND Life Sciences
0.07
0.00
0.00%
TSE:MOOD
Doseology Sciences
0.71
0.56
373.33%

Cybin Corporate Events

Business Operations and Strategy
Cybin CEO to Speak at Milken Institute Global Conference on Medical Breakthroughs
Neutral
May 1, 2025

Cybin announced that its CEO, Doug Drysdale, will participate in a panel discussion at the 28th Annual Milken Institute Global Conference, focusing on the global landscape and opportunities for medical breakthroughs. This participation highlights Cybin’s commitment to advancing mental healthcare and its role in the rapidly evolving field of neuropsychiatry, potentially impacting its industry positioning and stakeholder interests.

Spark’s Take on TSE:CYBN Stock

According to Spark, TipRanks’ AI Analyst, TSE:CYBN is a Underperform.

Cybin’s stock score is significantly impacted by its lack of revenue and continuous financial losses, resulting in a low valuation score. While technical indicators are neutral, positive corporate events indicate potential for future growth. However, current financial challenges remain the dominant concern.

To see Spark’s full report on TSE:CYBN stock, click here.

Product-Related AnnouncementsBusiness Operations and Strategy
Cybin Expands Strategic Partnerships for Phase 3 MDD Treatment Trials
Positive
Apr 23, 2025

Cybin has announced new strategic clinical site partnerships to support its multinational Phase 3 program, PARADIGM, evaluating CYB003 for the adjunctive treatment of Major Depressive Disorder (MDD). These partnerships, now totaling 18 sites, aim to enhance operational efficiency and patient recruitment, potentially reducing the time to trial completion. The APPROACH study will include approximately 45 clinical sites, with the second Phase 3 study, EMBRACE, expected to begin in mid-2025. This initiative underscores Cybin’s commitment to addressing the global mental health crisis and improving patient outcomes through innovative treatments.

Spark’s Take on TSE:CYBN Stock

According to Spark, TipRanks’ AI Analyst, TSE:CYBN is a Underperform.

Cybin’s stock score is low due to significant financial challenges, including no revenue and continuous losses. While the technical analysis is neutral, the valuation is negatively impacted by poor financial performance. Positive corporate events, like strategic partnerships, offer potential for future growth, but the current financial struggles outweigh these developments.

To see Spark’s full report on TSE:CYBN stock, click here.

Product-Related AnnouncementsBusiness Operations and Strategy
Cybin Partners with Osmind to Boost Commercial Readiness for Psychiatry Programs
Positive
Apr 21, 2025

Cybin has announced a strategic partnership with Osmind to accelerate the commercial preparation of its clinical-stage psychiatry programs. By leveraging Osmind’s extensive network of over 800 clinics and its point-of-care software, Cybin aims to enhance its operational infrastructure for the commercialization of its lead clinical programs, CYB003 and CYB004, targeting major depressive disorder and generalized anxiety disorder, respectively. This collaboration is expected to facilitate Cybin’s market penetration and support its mission to transform the treatment paradigm for mental health disorders, addressing the significant unmet needs in the mental health crisis.

Spark’s Take on TSE:CYBN Stock

According to Spark, TipRanks’ AI Analyst, TSE:CYBN is a Neutral.

Cybin’s overall score reflects its financial struggles with no revenue and sustained losses. While technical indicators are neutral, the company’s valuation is negatively impacted by its financial performance. However, the positive corporate event related to the PARADIGM program offers potential for future growth if the initiative succeeds.

To see Spark’s full report on TSE:CYBN stock, click here.

Product-Related AnnouncementsBusiness Operations and Strategy
Cybin Accelerates PARADIGM Program for Depression Treatment
Positive
Feb 11, 2025

Cybin has launched strategic clinical site partnerships to accelerate its PARADIGM program, a multinational Phase 3 initiative evaluating CYB003 for treating major depressive disorder. This program includes multiple studies across over 40 sites in the U.S. and Europe, with a significant addressable market of over 300 million people. With a robust drug development team and Breakthrough Therapy Designation from the FDA, Cybin aims to shift depression treatment towards more intermittent therapies rather than daily dosing.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 24, 2025