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Appili Therapeutics Inc Class A (TSE:APLI)
TSX:APLI
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Appili Therapeutics Inc Class A (APLI) AI Stock Analysis

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TSE:APLI

Appili Therapeutics Inc Class A

(TSX:APLI)

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Neutral 41 (OpenAI - 5.2)
Rating:41Neutral
Price Target:
C$0.01
▼(-30.00% Downside)
Action:Reiterated
Date:06/28/26
The score is primarily held down by weak financial performance—persistent losses, mostly negative cash flow, and a strained balance sheet with negative equity and rising debt. Technicals also lean bearish with the stock trading below key moving averages and negative MACD. Valuation contributes additional risk because a negative P/E reflects ongoing unprofitability and there is no dividend support.
Positive Factors
Focused infectious-disease pipeline
A narrow, clinical-stage focus on unmet infectious-disease indications creates durable strategic clarity. Specialization can improve R&D efficiency, make the company an attractive partner/licensing target, and align it with persistent public-health and funding priorities for antibacterials, antivirals, and antifungals.
Negative Factors
Strained balance sheet
Negative equity and rising debt materially weaken financial flexibility. Over time this increases financing costs, raises default or covenant risk, and makes the company reliant on dilutive financing or expensive borrowing, constraining its ability to fund development without external support.
Read all positive and negative factors
Positive Factors
Negative Factors
Focused infectious-disease pipeline
A narrow, clinical-stage focus on unmet infectious-disease indications creates durable strategic clarity. Specialization can improve R&D efficiency, make the company an attractive partner/licensing target, and align it with persistent public-health and funding priorities for antibacterials, antivirals, and antifungals.
Read all positive factors

Appili Therapeutics Inc Class A (APLI) vs. iShares MSCI Canada ETF (EWC)

Appili Therapeutics Inc Class A Business Overview & Revenue Model

Company Description
Appili Therapeutics Inc., a Canadian biopharmaceutical firm headquartered in Halifax and founded in 2015, specializes in sourcing and advancing innovative treatments to address critical gaps in infectious disease medicine. The company's diverse pi...
How the Company Makes Money
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Appili Therapeutics Inc Class A Financial Statement Overview

Summary
Financials remain weak: revenue is low and volatile, net income is negative in every year shown, and operating losses worsened in 2026. The balance sheet is a major risk with persistently negative equity and rising debt versus a small asset base. Cash flow is mostly negative (with only one positive operating cash flow year), indicating ongoing reliance on external funding despite some improvement versus the worst 2022–2023 burn.
Income Statement
22
Negative
Balance Sheet
12
Very Negative
Cash Flow
24
Negative
BreakdownMar 2026Mar 2025Mar 2024Mar 2023Mar 2022
Income Statement
Total Revenue244.18K100.44K827.41K334.18K1.39M
Gross Profit236.09K100.44K827.41K327.91K1.39M
EBITDA-6.53M360.57K-2.07M-8.10M-23.51M
Net Income-4.24M-2.62M-3.78M-9.24M-25.12M
Balance Sheet
Total Assets1.97M3.03M1.49M3.13M8.28M
Cash, Cash Equivalents and Short-Term Investments40.00K1.23M94.49K2.47M6.66M
Total Debt12.94M12.29M8.18M7.67M4.98M
Total Liabilities19.30M16.43M12.42M10.53M11.55M
Stockholders Equity-17.33M-13.40M-10.92M-7.40M-3.27M
Cash Flow
Free Cash Flow-1.38M866.46K-2.49M-10.10M-19.08M
Operating Cash Flow-1.38M868.82K-2.46M-10.10M-19.08M
Investing Cash Flow0.00-2.36K-29.06K-3.17K5.06M
Financing Cash Flow197.82K193.68K122.05K5.91M9.56M

Appili Therapeutics Inc Class A Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.02
Price Trends
50DMA
0.02
Negative
100DMA
0.02
Negative
200DMA
0.02
Negative
Market Momentum
MACD
>-0.01
Negative
RSI
45.75
Neutral
STOCH
100.00
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:APLI, the sentiment is Negative. The current price of 0.02 is above the 20-day moving average (MA) of 0.02, above the 50-day MA of 0.02, and below the 200-day MA of 0.02, indicating a bearish trend. The MACD of >-0.01 indicates Negative momentum. The RSI at 45.75 is Neutral, neither overbought nor oversold. The STOCH value of 100.00 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:APLI.

Appili Therapeutics Inc Class A Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
C$5.07M-0.19-111.11%-79.26%
44
Neutral
C$717.12K1.37-10.30%
42
Neutral
C$49.12M-13.73-31.89%21.88%
41
Neutral
C$1.93M-0.6319.73%140.47%-56.48%
41
Neutral
C$6.15M-2.38
C$2.04M-0.5925.09%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:APLI
Appili Therapeutics Inc Class A
0.02
0.00
0.00%
TSE:XRTX
XORTX Therapeutics Inc
2.93
-3.17
-51.97%
TSE:KNE
Kane Biotech
0.03
-0.02
-40.00%
TSE:MIR
Medmira
0.07
>-0.01
-10.26%
TSE:VXL
Vaxil Bio
0.18
-0.02
-10.00%
TSE:BIOV
BioVaxys Technology
0.07
-0.28
-80.00%

Appili Therapeutics Inc Class A Corporate Events

Business Operations and StrategyPrivate Placements and FinancingProduct-Related Announcements
Appili Therapeutics Targets New Funding and Partnerships at World Vaccine Congress Washington
Positive
Mar 30, 2026
Appili Therapeutics will exhibit at the World Vaccine Congress Washington 2026, where its CEO and chief development officer plan to highlight recent collaborations and funding milestones while seeking additional non-dilutive financing. The company...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 28, 2026