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Biogen (BIIB)
NASDAQ:BIIB

Biogen (BIIB) AI Stock Analysis

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BI

Biogen

(NASDAQ:BIIB)

70Outperform
Biogen's financial stability and strong cash flow are key strengths, but declining revenue and moderate ROE present challenges. The stock is technically weak, facing bearish trends. Valuation appears attractive with a low P/E ratio, suggesting potential undervaluation. Positive new product performance and operational efficiencies were notable in the earnings call, though challenges in the MS segment persist.
Positive Factors
Market Expansion
Biogen's exclusive commercialization rights for zorevunersen outside the U.S., Canada, and Mexico could increase its global market reach.
Regulatory Approvals
The European Commission has granted marketing authorization for Leqembi in the EU, potentially expanding its market reach.
Strategic Collaborations
Biogen's collaboration with Stoke Therapeutics to develop and commercialize zorevunersen could enhance its pipeline with a rare neuro asset at minimal upfront cost.
Negative Factors
Financial Performance
A second consecutive year of Total Revenue decline is modeled for Biogen, reflecting ongoing challenges.
Market Competition
NVO’s oral GLP-1A semaglutide data in early Alzheimer’s disease is an overhang on BIIB, casting uncertainty on its competitive position in Alzheimer's treatment.
Regulatory Challenges
Management anticipates a financial headwind of $50 million to $100 million due to changes in Medicare Part D, affecting both Skyclarys and the multiple sclerosis franchise.

Biogen (BIIB) vs. S&P 500 (SPY)

Biogen Business Overview & Revenue Model

Company DescriptionBiogen Inc. discovers, develops, manufactures, and delivers therapies for treating neurological and neurodegenerative diseases. The company offers TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, TYSABRI, and FAMPYRA for multiple sclerosis (MS); SPINRAZA for spinal muscular atrophy; and FUMADERM to treat plaque psoriasis. It also provides BENEPALI, an etanercept biosimilar referencing ENBREL; ADUHELM for the treatment of Alzheimer's disease; IMRALDI, an adalimumab biosimilar referencing HUMIRA; and FLIXABI, an infliximab biosimilar referencing REMICADE. In addition, the company offers RITUXAN for treating non-Hodgkin's lymphoma, chronic lymphocytic leukemia (CLL), rheumatoid arthritis, two forms of ANCA-associated vasculitis, and pemphigus vulgaris; RITUXAN HYCELA for non-Hodgkin's lymphoma and CLL; GAZYVA to treat CLL and follicular lymphoma; and OCREVUS for treating relapsing MS and primary progressive MS; and other anti-CD20 therapies. Further, it develops BIIB135, BIIB061, BIIB091, and BIIB107 for MS and neuroimmunology; Aducanumab, Lecanemab, BIIB076, and BIIB080 to treat Alzheimer's disease and dementia; BIIB067, BIIB078, BIIB105, BIIB100, and BIIB110 to treat neuromuscular disorders; BIIB124, BIIB094, BIIB118, BIIB101, and BIIB122 for treating Parkinson's disease and movement disorders; BIIB125 and BIIB104 for treating neuropsychiatry; Dapirolizumab pegol and BIIB059 to treat immunology related diseases; BIIB093 and BIIB131 to treat acute neurology; BIIB074 for neuropathic pain; and BYOOVIZ, BIIB800, and SB15 biosimilars, which are under various stages of development. The company has collaboration and license agreements with Acorda Therapeutics, Inc.; Alkermes Pharma Ireland Limited; Denali Therapeutics Inc.; Eisai Co., Ltd.; Genentech, Inc.; Neurimmune SubOne AG; Ionis Pharmaceuticals, Inc.; Samsung Bioepis Co., Ltd.; Sangamo Therapeutics, Inc.; and Sage Therapeutics, Inc. Biogen Inc. was founded in 1978 and is headquartered in Cambridge, Massachusetts.
How the Company Makes MoneyBiogen generates revenue primarily through the sale of its pharmaceutical products, which are aimed at treating neurological and neurodegenerative diseases. Key revenue streams include its multiple sclerosis franchise, featuring notable products such as Tecfidera, Avonex, and Tysabri, which have been significant contributors to the company's earnings. Additionally, Biogen has invested in the development of treatments for Alzheimer's disease, with products like Aduhelm aimed at addressing unmet medical needs in this area. The company also engages in strategic collaborations and partnerships, which can offer both financial support and expanded market reach. Biogen's revenue model is heavily reliant on the success and market penetration of its therapies, as well as continuous innovation to maintain its competitive edge in the biotechnology industry.

Biogen Financial Statement Overview

Summary
Biogen presents a financially stable outlook with strong profitability margins and a robust cash flow position. The balance sheet is solid with low leverage, enhancing financial resilience. However, the declining revenue trend and moderate return on equity suggest areas for improvement. The company should focus on reversing revenue decline and optimizing cost structures to enhance net profitability.
Income Statement
65
Positive
Biogen's TTM (Trailing-Twelve-Months) income statement shows mixed results. The gross profit margin is healthy at 78.53%, reflecting strong operational efficiency. However, the net profit margin has decreased to 17.23%, indicating rising costs or competitive pressures. Revenue has seen a negative growth rate of -3.68%, suggesting a decline in sales over the previous year. The EBIT margin of 30.99% and EBITDA margin of 24.22% showcase solid profitability, but the declining revenue trend is a concern.
Balance Sheet
70
Positive
Biogen's balance sheet indicates a stable financial position with a debt-to-equity ratio of 0.28, suggesting low leverage. The return on equity (ROE) is 9.35%, which is moderate but has room for improvement. The equity ratio stands at 62.19%, indicating a strong equity base relative to total assets. Overall, the company maintains a solid capital structure with manageable debt levels.
Cash Flow
75
Positive
The cash flow analysis is positive with a significant increase in free cash flow to $2.62 billion, indicating robust cash generation. The free cash flow growth rate is 112.13%, driven by improved operational efficiencies. The operating cash flow to net income ratio of 1.76 and a free cash flow to net income ratio of 1.61 highlight strong cash generation capabilities relative to profits, providing financial flexibility.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
9.68B9.84B10.17B10.98B13.44B
Gross Profit
9.68B7.30B7.90B8.87B11.64B
EBIT
5.23B2.10B2.32B2.84B4.55B
EBITDA
0.002.38B4.36B2.49B5.73B
Net Income Common Stockholders
1.63B1.16B3.05B1.56B4.00B
Balance SheetCash, Cash Equivalents and Short-Term Investments
2.38B1.05B4.89B3.80B2.61B
Total Assets
28.05B26.84B24.55B23.88B24.62B
Total Debt
6.63B7.34B6.61B7.60B7.83B
Net Debt
4.26B6.29B3.19B5.34B6.50B
Total Liabilities
11.33B12.05B11.17B12.92B13.93B
Stockholders Equity
16.72B14.80B13.39B10.96B10.69B
Cash FlowFree Cash Flow
2.52B1.24B1.14B3.35B3.68B
Operating Cash Flow
2.88B1.55B1.38B3.64B4.23B
Investing Cash Flow
-799.20M-4.10B1.58B-563.70M-608.60M
Financing Cash Flow
-683.50M149.30M-1.76B-2.09B-5.27B

Biogen Technical Analysis

Technical Analysis Sentiment
Negative
Last Price118.84
Price Trends
50DMA
133.65
Negative
100DMA
141.22
Negative
200DMA
167.77
Negative
Market Momentum
MACD
-5.07
Negative
RSI
40.59
Neutral
STOCH
68.15
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BIIB, the sentiment is Negative. The current price of 118.84 is below the 20-day moving average (MA) of 121.83, below the 50-day MA of 133.65, and below the 200-day MA of 167.77, indicating a bearish trend. The MACD of -5.07 indicates Negative momentum. The RSI at 40.59 is Neutral, neither overbought nor oversold. The STOCH value of 68.15 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BIIB.

Biogen Risk Analysis

Biogen disclosed 30 risk factors in its most recent earnings report. Biogen reported the most risks in the “Finance & Corporate” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Biogen Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
SNSNY
74
Outperform
$125.03B21.437.34%2.82%-4.57%2.96%
73
Outperform
$128.62B22.3432.58%3.00%4.71%1144.01%
70
Outperform
$17.40B10.6310.36%-1.60%39.71%
GSGSK
65
Neutral
$74.87B23.2319.11%4.08%6.28%-47.11%
BMBMY
63
Neutral
$103.18B31.99%5.05%4.62%
60
Neutral
$150.99B37.0267.55%3.25%18.64%-39.39%
51
Neutral
$5.32B3.39-40.26%2.89%17.93%2.48%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BIIB
Biogen
118.84
-96.66
-44.85%
AMGN
Amgen
280.84
12.64
4.71%
BMY
Bristol-Myers Squibb
47.90
5.35
12.57%
GILD
Gilead Sciences
103.17
39.62
62.34%
GSK
GlaxoSmithKline
37.43
-2.60
-6.50%
SNY
Sanofi
52.32
4.68
9.82%

Biogen Earnings Call Summary

Earnings Call Date: Feb 12, 2025 | % Change Since: -14.74% | Next Earnings Date: May 1, 2025
Earnings Call Sentiment Neutral
Biogen's earnings call highlighted successful new product launches and operational efficiency, offsetting declines in its multiple sclerosis franchise. However, challenges persist in identifying patients for SKYCLARYS and pressure on MS revenues is expected to continue.
Highlights
New Product Launch Success
Revenue from new launches in Alzheimer's, Friedreich’s ataxia, depression, and ALS offset declines in multiple sclerosis products. Core pharma business grew for the first time in four years, despite a $160 million decline in total revenue.
LEQEMBI Growth
LEQEMBI global in-market sales increased approximately 30% sequentially to $87 million in Q4 2024, driven by strong growth in Asia and facilitated by a single-payer system ex-US.
SKYCLARYS Expansion
SKYCLARYS revenue grew 83% year-over-year to $102 million in Q4 2024. Patient numbers have doubled, with expectations for continued growth in Latin America and the Middle East.
Operational Efficiency
Fit for Growth initiative contributed to a 17% increase in non-GAAP diluted EPS in Q4 2024. Free cash flow improved by $1.4 billion year-over-year, reaching $2.7 billion.
Lowlights
Multiple Sclerosis Revenue Decline
MS product revenue declined 8% due to competition and expected biosimilar entry for TYSABRI in the U.S. and generics for TECFIDERA in Europe.
Revenue Guidance Decline
Biogen expects a mid-single-digit percentage decline in total revenue for 2025, driven by increased pressure on the MS business.
Challenges in Patient Identification
Difficulty in identifying patients for SKYCLARYS in the U.S. due to the rarity of Friedreich’s ataxia and the wide prescriber base needed.
Company Guidance
During Biogen's fourth quarter and full year 2024 earnings call, the company emphasized its strategic priorities and financial performance. They reported a total revenue decline of $160 million, attributed mainly to a $247 million reduction in contract manufacturing, while their core pharmaceutical business demonstrated growth. The decline in multiple sclerosis (MS) product revenue was offset by new product launches, and the overall revenue was $9.7 billion for the year. The company highlighted the importance of its new products in Alzheimer's, Friedreich’s ataxia, depression, and ALS, with LEQEMBI showing promising signs of growth. Biogen also announced a reduction in operating expenses and a commitment to reinvest in growth, resulting in $722 million of free cash flow in the fourth quarter. The company projected a mid-single-digit percentage decline in total revenue for 2025, primarily due to increased competition in the MS space, but expected continued strong growth from new product launches. Non-GAAP diluted earnings per share for 2025 are expected to be between $15.25 and $16.25, with $180 million to $220 million in net expense from non-GAAP other income and expense.

Biogen Corporate Events

Executive/Board Changes
Biogen Announces New Chief Accounting Officer Appointment
Neutral
Jan 15, 2025

On January 13, 2025, Biogen Inc. announced the appointment of Sean Godbout as Vice President, Chief Accounting Officer & Global Corporate Controller, effective March 1, 2025. This appointment aligns with the retirement of current Chief Financial Officer Michael McDonnell, after which Robin Kramer, the current Chief Accounting Officer, will transition to the CFO role. Godbout’s extensive experience within Biogen since 2007, and his previous roles at PricewaterhouseCoopers, underline his qualifications for this new position, potentially impacting Biogen’s financial strategy and operations.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.