Annual Revenue and Adjusted EBITDA (2025) and 2026 Guidance
Organon delivered $6.2 billion of revenue and $1.9 billion of adjusted EBITDA in 2025 (revenue down ~3% year-over-year reported and ex-FX). Management guides to roughly flat results for 2026 (about $6.2B revenue and ~$1.9B adjusted EBITDA), signaling stability at current run-rate.
Strong Biosimilars Performance (Hadlima & New Launches)
Hadlima grew ~61% ex-FX globally in 2025. Biosimilars benefited from new denosumab launches and the Tofidence acquisition; management expects biosimilars to deliver flat to modest growth in 2026 as new assets offset declines in Ontruzan and Renflexis.
Vtama, Emgality and Fertility Growth Offsetting Other Headwinds
Vtama delivered $128 million of global revenue in 2025. Emgality and the fertility business showed strong growth (fertility +8% ex-FX full year), and together these products helped offset LOE and respiratory pressure.
Nexplanon Regulatory Milestone — 3 to 5 Year Approval
FDA approved sNDA extending Nexplanon duration from 3 to 5 years, expanding addressable market (including higher-BMI populations) and adding a new REMS program — a meaningful product-level strategic win for long-term growth.
Material Cost Savings and Margin Management
Organon achieved over $200 million in cost savings in 2025 (reference to a ~$275M gross cost takeout target). Adjusted EBITDA margin for the full year remained ~30.7%, essentially flat with 2024 despite ~150 bps gross margin degradation, reflecting successful cost control.
Free Cash Flow, Divestiture and Deleveraging Progress
Generated $960 million of free cash flow in 2025 (consistent with prior year). Divested the Jada system for ~ $390 million net proceeds (completed Jan 2026) and retired ~ $530 million of debt in 2025. Net leverage was ~4.3x year-end with management targeting below 4.0x by end-2026.
Operational Actions to Prioritize Balance Sheet
Company lowered dividend payout ratio to accelerate debt reduction, discontinued early-stage clinical programs and limited certain R&D investments to preserve capital and focus on marketed products.