Revenue Growth
Vertex delivered $3.08 billion in revenue, reflecting double-digit growth versus Q3 2024, driven by strong performance across its portfolio.
ALYFTREK Expansion
ALYFTREK, which launched in the U.S. late last year, has shown strong uptake, especially among patients naive to CFTR modulators, with nearly 10x as many newly eligible patients in Europe compared to the U.S.
CASGEVY Revenue Milestone
CASGEVY is on track for over $100 million in revenue this year, with significant growth expected in 2026.
JOURNAVX Prescription Growth
More than 300,000 prescriptions for JOURNAVX have been filled as of mid-October, indicating strong market uptake.
Pipeline Progress
Vertex has several programs in Phase III development, including povetacicept for IgAN, which has received breakthrough therapy designation and is on track for potential accelerated approval.
Strong Financial Performance
Q3 2025 non-GAAP net income was $1.24 billion, a 10% increase from Q3 2024, with a non-GAAP earnings per share increase of 10%.