Lonvo-z Phase III Clinical Trial Progress
Enrollment for the HAELO Phase III clinical trial for HAE was completed in September 2025, putting Intellia on track to share top line data by mid-2026, submit a BLA in the second half of 2026, and anticipate commercial launch in the U.S. in the first half of 2027.
Financial Position and Extended Cash Runway
Intellia Therapeutics maintains a solid balance sheet with cash, cash equivalents, and marketable securities at $669.9 million as of September 30, 2025. Through restructuring and ATM facility, cash runway extended into mid-2027, aligning with lonvo-z's anticipated U.S. commercial launch.
Increased Collaboration Revenue
Intellia's collaboration revenue increased to $13.8 million during the third quarter of 2025, up from $9.1 million in the prior year quarter, primarily driven by cost reimbursements from Regeneron Pharmaceuticals.