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Wave Life Sciences price target lowered to $18 from $21 at Wells Fargo

Wells Fargo analyst Tiago Fauth lowered the firm’s price target on Wave Life Sciences (WVE) to $18 from $21 and keeps an Overweight rating on the shares after the company reported AATD data update for 200 and 400 cohort. While the data support ‘006’s MoA, they do not clearly answer whether ‘006 can increase M-AAT levels to the 11microM+ threshold most investors were hoping for and potential positioning vs competitive landscape/modalities.

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