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Spyre Therapeutics upgraded to Buy from Hold at JonesResearch

JonesResearch analyst Debanjana Chatterjee upgraded Spyre Therapeutics (SYRE) to Buy from Hold with a $64 price target The company reported positive data from the Phase 1 healthy volunteer trial of SPY003, the analyst tells investors in a research note. Ahead of updates in 2026, the firm believes the stock’s risk/reward “now skews positive.”

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