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Spyre Therapeutics initiated with an Outperform at Mizuho

Mizuho initiated coverage of Spyre Therapeutics (SYRE) with an Outperform rating and $53 price target The firm believes the company’s half-life extended monoclonal antibody pipeline as positioned to play a “significant role” in inflammatory bowel disease. The company’s more compelling opportunity is its ability to evaluate novel combinations, the analyst tells investors in a research note. It projects risk-adjusted worldwide sales of $1.7B in 2035.

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