Simulations Plus teams with ETC to advance IVIVC in drug delivery

Simulations Plus (SLP) announced that it has entered a new funded collaboration with the Enabling Technologies Consortium ETC . This partnership is aimed at advancing in vitro-in vivo correlation or IVIVC, approaches for oral drug delivery and expanding the functionality of the GastroPlus platform. The collaboration focuses on enhancing the predictive capabilities of the GastroPlus advanced compartmental absorption and transit model to support the development of immediate release oral drug products. Using data gathered from public sources and members of the ETC, physiologically based pharmacokinetics or PBPK and biopharmaceutics modeling xperts and software engineers at Simulations Plus will look to complete key objectives as defined by the partnership. These advancements, including implementation of novel product-particle size distribution methodologies and enhanced food effect modeling features, will provide researchers with powerful tools to improve drug product development, reduce reliance on animal studies, and streamline regulatory submissions. ”