Plus Therapeutics (PSTV) announced the treatment of its initial patients in the Company’s ReSPECT-LM dose optimization trial for REYOBIQ for the treatment of leptomeningeal metastases. The dose optimization trial builds on results from the Company’s completed Phase 1 single-dose escalation study, which demonstrated the feasibility of REYOBIQ for treating LM. The trial is designed in alignment with the FDA’s Project Optimus to identify the optimal dosing regimen that maximizes efficacy and safety.
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