Pfizer announces three settlement agreements for Vyndamax

Pfizer (PFE) announced that it has entered into settlement agreements with generic drug manufacturers Dexcel Pharma, Hikma Pharmaceuticals and Cipla Ltd, regarding lawsuits filed in the U.S. District Court for the District of Delaware for infringement of patents relating to Vyndamax, or tafamidis, a treatment for cardiomyopathy transthyretin-mediated amyloidosis. These settlements extend the effective U.S. patent expiry date for Vyndamax to June 1, 2031, subject to the outcome of other litigation. Pfizer had previously anticipated a significant decline in U.S. revenues for Vyndamax beginning in 2029 upon patent expiry. As a result of this settlement, revenues are now expected to remain relatively stable from 2028 through mid-2031, the company stated. “We are very pleased by this outcome, both for patients and in recognition of the value of our innovative science and the strength of our patents,” said Aamir Malik, Executive Vice President and Chief U.S. Commercial Officer, Pfizer. “Our focus continues to be our unwavering commitment to patients with ATTR-CM. With our market leadership and physician experience, we remain confident in the value and benefits of Vyndamax as we work to reach more patients living with this serious and underdiagnosed disease.”