PacBio partners with Target ALS to launch genome sequencing initiative

Target ALS has partnered with PacBio (PACB) to launch the largest global whole genome sequencing initiative for ALS to date. By applying PacBio’s HiFi sequencing to more than 6,000 genomes from people with ALS and healthy controls, the project aims to detect structural variants, repeat expansions, and other hard-to-detect genetic features that may underlie the disease. As part of the ALS Global Research Initiative, all data will be openly shared via the Target ALS Data Engine, removing barriers to access and enabling researchers around the world to uncover disease mechanisms and explore new pathways to treatment.