PacBio (PACB) announced that Basecamp Research, a frontier AI lab for therapeutic design, has selected PacBio HiFi sequencing on the Revio system to generate large-scale environmental and host-associated metagenomic data for the Trillion Gene Atlas-a landmark scientific initiative designed to generate and model biological data at the trillion-gene scale. The collaboration is expected to result in approximately 100,000 deeply sequenced samples from over 31 countries across 5 continents, creating the largest and most diverse high-fidelity metagenomic dataset assembled to date. As AI models for biological design advance, model performance increasingly depends on the diversity, quality, and genomic context of training data. Basecamp’s Environmentally-Derived Evolutionary Network model leverages large-scale evolutionary metagenomic data to capture biological signals often missing from curated reference genomes-particularly when long-range genomic context is preserved. PacBio HiFi sequencing combines high accuracy with long reads to resolve complex genomes and microbial communities.
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