Omada Health announces analysis on weight maintenance post GLP-1 discontinuation

Omada Health (OMDA) released results from a real-world analysis that showed 63% of Omada members maintained or continued to lose weight 12 months after discontinuing GLP-1s,1 challenging widespread assumptions of inevitable post-medication weight regain. Since the GLP-1 Care Track launched, Omada has supported more than 100,000 members taking GLP-1 medications. The retrospective analysis included 816 members in Omada’s GLP-1 Care Track and examined GLP-1 discontinuation and subsequent weight change at 6, 9, and 12 months.1 At one year post-discontinuation members showed just 0.8% average weight change,1 compared to 11-12% weight gain typically seen in clinical trials2-3 where participants do not always have access to wraparound lifestyle support after they stop the medication.3 Omada’s analysis demonstrated participants largely experienced weight maintenance consistently throughout the year, with 0.03% average weight change at 6 months and 0.6% average weight change at 9 months,1 suggesting the sustained impact of lifestyle support at this critical moment in their GLP-1 journey. The analysis used claims-based methodology to track outcomes of members without diabetes enrolled in Omada’s GLP-1 Care Track at 6, 9, and 12 months post-discontinuation. Omada offers behavioral support through dedicated care teams alongside connected devices and an AI-enhanced digital experience. Omada’s program emphasizes the importance of maintaining muscle mass in members’ GLP-1 journeys, through activity and movement guidance for a holistic approach to weight health.