Nautilus Biotechnology (NAUT) announced Baylor College of Medicine as the first customer of Nautilus’ Iterative Mapping Early Access Program. Through a National Institutes of Health, or NIH, U01-funded study, Baylor will leverage Nautilus’ novel single-molecule proteomics method to address a central challenge in cancer research – identifying aberrant protein isoforms that contribute to tumor growth, metastasis, immune evasion, and therapeutic resistance – while Nautilus expands early commercial access to its validated tau proteoforms assay. The study aims to develop a broadly accessible computational toolkit with improved detection of protein isoforms in conventional shotgun proteomics datasets. By pairing these computational approaches with full-length, isoform-resolved proteomic measurements generated on the Nautilus Voyager Platform, the project is intended to enable direct comparison of transcriptional and proteomic changes at unprecedented resolution.
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