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Mereo BioPharma downgraded to Neutral from Overweight at JPMorgan

JPMorgan on Friday night downgraded Mereo BioPharma (MREO) to Neutral from Overweight without a price target The firm cites the uncertainty of the regulatory process for the company’s setrusumab program for the downgrade. The Phase 3 ORBIT and COSMIC trials of setrusumab in osteogenesis imperfecta missed their primary endpoints of annualized fracture rate, the analyst tells investors in a research note.

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