Leerink notes that Compass Therapeutics (CMPX) announced progression free survival and overall survival results for tovecimig in second line biliary tract cancer from the randomized COMPANION-002 study. At a high level, the firm views this data update as supportive of a path forward in an area of high unmet need. Recall, Compass is evaluating tovecimig plus paclitaxel vs. paclitaxel in the Phase II/III COMPANION-002 study for second line biliary tract cancer. Leerink views today’s updates as supportive of a path forward for tovecimig in second line BTC where no labeled treatment is available. Nonetheless, the firm believes investors will want to understand the impact of the crossover on OS results, the implications of the posthoc OS analyses, and the regulatory steps moving forward. Leerink has an Outperform rating on the shares.
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