Journey Medical (DERM) Corporation presented efficacy data from a pooled analysis of the two Phase 3 multicenter, randomized, double-blind, parallel-group, active-comparator and placebo-controlled clinical trials, Minocycline Versus Oracea in Rosacea-1 and Minocycline Versus Oracea in Rosacea-2 , evaluating DFD-29 for the treatment of inflammatory lesions of rosacea in adults, at the 2025 Fall Clinical Dermatology Conference taking place October 23-26, 2025, in Las Vegas, NV. In the Phase 3 study, 62.7% of subjects treated with DFD-29 achieved IGA treatment success, compared with 39.0% in the Oracea group and 28.2% in the placebo group. The differences between the DFD-29 and both Oracea and placebo were statistically significant, each with a p-value of less than0.001. The DFD-29 group also experienced a mean reduction of 19.2 inflammatory lesions from baseline to week 16, versus reductions of 14.8 lesions with Oracea and 11.3 lesions with placebo.
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