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JonesResearch upgrades ‘fast-follower’ Korro Bio to Buy

As previously reported, JonesResearch analyst Catherine Novack upgraded Korro Bio (KRRO) to Buy from Hold with a $23 price target after the company reported Q1 results. While both Korro’s GalNAc-conjugated RNA editor for alpha-1 antitrypsin deficiency and KRRO-121 for urea cycle disorders are likely greater than 12 months from clinical data, the firm likes the upside on the AATD program and notes that some positive readthrough could be seen from a competing base editing program from Wave Life Sciences (WVE). Korro “also has fast-follower advantage” as Wave and Beam Therapeutics (BEAM) define the regulatory path for genetic medicine in AATD.

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