HUTCHMED (HCM) announced key research and development, R&D, and business updates presented during its R&D Updates event held on October 31, 2025. The event highlighted HUTCHMED’s progress in advancing innovative cancer and immunology treatments, including the introduction of its next-generation Antibody-Targeted Therapy Conjugate, ATTC, platform, alongside updates on late-stage pipeline candidates. Key points: HUTCHMED unveils its ATTC platform, potentially providing precision oncology with synergistic dual-mechanism of action; Lead candidate HMPL-A251 harnesses a selective PI3K/PIKK inhibitor payload, demonstrating promising preclinical efficacy and safety; Progress in global and China trials, including FRUSICA-2, SANOVO, surufatinib’s PDAC and fanregratinib’s IHCC studies, advances HUTCHMED’s late-stage pipeline.
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