Elutia announces publication of new study on CIED biologic envelope

Elutia (ELUT) announced the publication of a new study describing the bioinductive effects of its antibiotic-eluting CIED biologic envelope in the Journal of Functional Biomaterials. Researchers from the Department of Cardiac Sciences at the Cumming School of Medicine found that the biomatrix in EluPro controlled inflammation and supported vascularization, key to a healthy device pocket with less scarring and risk of infection. In mechanistic studies, fibroblasts, cells critical for tissue repair and healing, released significantly higher levels of growth and wound healing factors in the biomatrix environment compared to controls. These effects were further supported by long-term animal studies, where the biomatrix promoted blood vessel formation and reduced inflammation and scarring over a 26-week period. In contrast, synthetic polymer materials exhibited persistent inflammation and fibrosis.