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Centessa initiated with an Overweight at Piper Sandler

Piper Sandler analyst Biren Amin initiated coverage of Centessa (CNTA) with an Overweight rating and $38 price target The company is developing a multi-asset orexin receptor 2 agonist franchise to address excessive daytime sleepiness, fatigue, impaired attention, and cognitive defects across neurodegenerative and neuropsychiatric disorders, the analyst tells investors in a research note. The firm believes orexin agonists “have wide reaching potential.” Centessa’s ORX750 is a potential best-in-class OX2R Agonist and the upcoming Phase 2a data in 2025 “represents a major catalyst,” contends Piper.

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