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BofA upgrades Pharvaris to Neutral on potential label expansion

As previously reported, BofA upgraded Pharvaris (PHVS) to Neutral from Underperform with a price target of $27, up from $16. Pharvaris is targeting a broad label for its drug to treat bradykinin-mediated angioedema, while most competitors are only approved for hereditary angioedema type 1/2, notes the analyst, who says success in this strategy would make it the only company with an oral option for both acute and preventative treatment. However, the firm thinks the current valuation assumes significant value for upcoming acute HAE data and that the prophylactic opportunity “still needs de-risking,” the analyst added.

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