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Black Diamond Therapeutics downgraded to Neutral from Buy at Guggenheim

Guggenheim analyst Brad Canino downgraded Black Diamond Therapeutics (BDTX) to Neutral from Buy without a price target While the headline overall response rate in the silevertinib 1L non-classical EGFRm phase 2 trial is “competitive,” there was very high toxicity and there are questions around potential durability, the analyst tells investors in a research note. The firm sees risk to the 2Q26 progression free survival catalyst and Phase 3 start up execution.

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