Bausch + Lomb (BLCO) announced that Ophthalmology and Therapy published a narrative review highlighting the role of certain B vitamins in reducing the risk of development and progression of AMD, a leading cause of vision loss in Americans 50 years of age or older. Key clinical insights from the paper: Women’s Antioxidant and Folic Acid Cardiovascular Study demonstrated a 34% reduction in AMD risk and a 41% reduction in visually significant AMD with daily supplementation of specific concentrations of B6, B9 and B12; AREDS and AREDS2 post-hoc analyses showed decreased risk of progression to geographic atrophy and neovascular AMD with higher dietary intake of B6 and B9; The Blue Mountains Eye Study and Alienor Study linked low serum B12 and B9 levels to increased AMD incidence and progression, highlighting the importance of maintaining adequate B vitamin levels; Across epidemiologic, mechanistic and randomized clinical trial data, findings consistently show that B vitamin levels and function are closely tied to both AMD risk and disease progression
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