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Amgen price target raised to $381 from $342 at Piper Sandler

Piper Sandler raised the firm’s price target on Amgen (AMGN) to $381 from $342 and keeps an Overweight rating on the shares. The firm notes monthly third-party prescription data for October 2025 became available recently, and this piece highlights Rx data and trends for a number of key Amgen products. Looking at Repatha and Tezspire more specifically, Piper continues to believe that visibility into aggressive volume growth for both products is high.

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