Alzamend Neuro reports ‘positive’ data from Phase II clinical trial of AL001

Alzamend Neuro (ALZN) announced positive topline data from its first Phase II “Lithium in Brain” clinical trial in healthy human subjects, demonstrating that AL001 meets bioequivalence standards while also showing numerically superior lithium delivery to the brain compared to standard lithium carbonate across all 26 measured brain regions including whole brain. These results suggest a promising differentiated pharmacological profile with significant implications for patients with Alzheimer’s, BD, MDD and PTSD. The trial was conducted at Massachusetts General Hospital and represents a meaningful clinical and regulatory advance for AL001. Bioequivalence Confirmed: AL001 delivered 101% of total lithium blood exposure and 97% of peak lithium levels vs. standard lithium carbonate. Superior Brain Penetration: AL001 showed numerically higher lithium concentrations in all measured brain regions, including whole brain. Faster Brain Uptake: AL001 reached peak brain concentration in 6.7 hours vs. 8.4 hours for standard lithium carbonate.