Akari Therapeutics (AKTX) announced the acceptance of an Australian patent covering its core payload technology, and further expanding protection of its proprietary ADC platform. The accepted patent includes composition-of-matter claims covering proprietary analogs of Thailanstatin designed for use as cytotoxic ADC therapeutics. This patent contains broad claims covering the use of these proprietary splicing payloads with ADC linkers and may be used to target different proteins on the cancer cell. Akari’s growing pipeline of novel ADCs including AKTX-101 and AKTX-102 all use the PH1 payload that is built around this novel IP.
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