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Optimistic Buy Rating for Structure Therapeutics Driven by Aleniglipron’s Potential in Obesity and T2D Markets

Optimistic Buy Rating for Structure Therapeutics Driven by Aleniglipron’s Potential in Obesity and T2D Markets

Analyst Patrick Dolezal of LifeSci Capital maintained a Buy rating on Structure Therapeutics, Inc. Sponsored ADR, with a price target of $75.00.

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Patrick Dolezal has given his Buy rating due to a combination of factors, primarily focusing on the potential of Structure Therapeutics’ lead asset, aleniglipron. As an oral, small molecule GLP-1 receptor agonist, aleniglipron is being developed for obesity and type 2 diabetes (T2D), and the upcoming Phase IIb data from the ACCESS and ACCESS-2 studies are expected to be significant catalysts for the company’s stock. Dolezal anticipates that the data could lead to a substantial increase in share value, potentially moving 100-200% upward, or a decrease of around 50%, depending on the outcomes.
Moreover, Dolezal highlights the competitive positioning of aleniglipron, which could become the second approved oral GLP-1 receptor agonist without a fasting requirement. This positions it favorably against competitors like Lilly’s orfoglipron, especially if aleniglipron’s therapeutic profile is comparable or superior. The analyst assigns a 50% probability of success for aleniglipron and estimates significant probability-adjusted peak sales in both obesity and T2D markets. These factors contribute to the optimistic outlook and the Buy rating for Structure Therapeutics.

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