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Exelixis: Solid Q4 Execution and Advancing Pipeline Underpin Buy Rating and 2026 Earnings Power

Exelixis: Solid Q4 Execution and Advancing Pipeline Underpin Buy Rating and 2026 Earnings Power

William Blair analyst Andy Hsieh has maintained their bullish stance on EXEL stock, giving a Buy rating on February 3.

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Andy Hsieh has given his Buy rating due to a combination of factors tied to Exelixis’ solid operating performance and clear growth trajectory. Fourth-quarter product revenue, led by Cabometyx, came in essentially as expected, with favorable gross‑to‑net dynamics more than offsetting temporary inventory effects, and adjusted earnings exceeded prior forecasts, underscoring strong underlying profitability.

Looking ahead, Hsieh highlights 2026 as a potentially pivotal year, with Exelixis’ updated guidance and refined financial model pointing to sustainable earnings power. He also emphasizes the advancing zanzalintinib program, which is moving toward key Phase III readouts and regulatory milestones, positioning the company for an additional revenue driver and supporting an attractive risk‑reward profile at current valuation levels.

In another report released on February 3, H.C. Wainwright also reiterated a Buy rating on the stock with a $52.00 price target.

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