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Cautious Outlook for CytomX Therapeutics Amid Pipeline Challenges and Strategic Setbacks

Cautious Outlook for CytomX Therapeutics Amid Pipeline Challenges and Strategic Setbacks

H.C. Wainwright analyst Mitchell Kapoor has reiterated their neutral stance on CTMX stock, giving a Hold rating on March 4.

Mitchell Kapoor has given his Hold rating due to a combination of factors impacting CytomX Therapeutics. The discontinuation of the CX-904 program, despite initial positive data in pancreatic cancer, highlights ongoing challenges in their pipeline, particularly in tough-to-treat indications. This decision, made jointly with Amgen, reflects the clinical observations and strategic priorities of both parties, adding to a history of setbacks in advancing PROBODY-based programs.
Furthermore, while the upcoming CX-2051 data in metastatic colorectal cancer could provide a pivotal update, the low benchmark for success in this area tempers expectations. The potential for underwhelming response rates, coupled with CytomX’s negative enterprise value, suggests a cautious outlook. Despite better-than-expected financial results for FY2024, Kapoor remains neutral, awaiting more substantial clinical data to reassess the opportunity for CTMX shares.

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