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4D Molecular Therapeutics: Strong Buy Rating on Promising 4D-150 Gene Therapy Data and Strategic Phase 3 Trials

4D Molecular Therapeutics: Strong Buy Rating on Promising 4D-150 Gene Therapy Data and Strategic Phase 3 Trials

Analyst Matthew Caufield of H.C. Wainwright reiterated a Buy rating on 4D Molecular Therapeutics (FDMTResearch Report), retaining the price target of $36.00.

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Matthew Caufield has given his Buy rating due to a combination of factors, primarily centered around 4D Molecular Therapeutics’ promising data from its Phase 2b PRISM trial for the 4D-150 gene therapy candidate targeting wet AMD. The trial data indicates significant clinical benefit with robust reduction in supplemental aflibercept injections and a noteworthy portion of patients achieving injection freedom, highlighting the therapy’s potential to reduce treatment burden.
Additionally, the upcoming Phase 3 4FRONT trials are strategically designed to further assess efficacy in both treatment-naïve and previously treated patients, which strengthens the case for 4D-150’s differentiated profile. The safety profile of 4D-150 is also favorable, with low incidence of inflammation and a manageable safety profile comparable to standard anti-VEGF treatments. These positive aspects underpin the reiteration of a Buy rating and a price target of $36.

In another report released today, Barclays also maintained a Buy rating on the stock with a $45.00 price target.

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