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XOMA Royalty Reports Strong 2025 Results and Growth

Story Highlights
  • XOMA Royalty delivered strong 2025 financials, boosting cash receipts and buybacks while generating positive operating cash flow.
  • The company significantly expanded its royalty portfolio and set up major 2026 clinical and regulatory catalysts to diversify future cash flows.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
XOMA Royalty Reports Strong 2025 Results and Growth

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XOMA Royalty Corporation ( (XOMA) ) has shared an announcement.

On March 18, 2026, XOMA Royalty reported its fourth-quarter and full-year 2025 results, posting $50.5 million in cash receipts, including $33.6 million in royalties and $16.9 million in milestones, a 9% increase in total receipts and a 68% jump in royalties versus 2024. The company achieved positive cash flow from operations, repurchased $16 million of its stock, and highlighted a growing base of commercial royalties from products such as VABYSMO and OJEMDA.

During 2025 and early 2026, XOMA expanded its portfolio by adding 22 assets and two platform technologies, completing or structuring seven acquisitions and amending its collaboration with Takeda to secure royalty and milestone rights across nine development-stage assets. With 14 programs now in registrational studies and key 2026 readouts and regulatory milestones expected for assets including volixibat, ersodetug, seralutinib, OJEMDA, and MIPLYFFA, the company signaled a potentially broader and more diversified royalty stream that could enhance free cash flow and shareholder value over the coming years.

The most recent analyst rating on (XOMA) stock is a Buy with a $50.00 price target. To see the full list of analyst forecasts on XOMA Royalty Corporation stock, see the XOMA Stock Forecast page.

Spark’s Take on XOMA Stock

According to Spark, TipRanks’ AI Analyst, XOMA is a Neutral.

Overall score reflects mixed financial performance (strong margins but elevated leverage and weak cash-flow trends) as the primary driver, with neutral technical signals and a high P/E weighing on the outlook; positive corporate developments provide a modest offset.

To see Spark’s full report on XOMA stock, click here.

More about XOMA Royalty Corporation

XOMA Royalty Corporation, based in Emeryville, Calif., is a biotech royalty aggregator that acquires economic interests in biopharmaceutical royalties and milestones. The company focuses on commercial and late-stage clinical assets across multiple therapeutic areas, seeking diversified, non-dilutive cash flows from partnered programs worldwide.

Average Trading Volume: 412,316

Technical Sentiment Signal: Sell

Current Market Cap: $334.3M

For a thorough assessment of XOMA stock, go to TipRanks’ Stock Analysis page.

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