Wave Life Sciences Pte. Ltd ( (WVE) ) has released its Q2 earnings. Here is a breakdown of the information Wave Life Sciences Pte. Ltd presented to its investors.
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Wave Life Sciences Ltd., a clinical-stage biotechnology company, is focused on developing RNA medicines to transform human health, with a diverse pipeline targeting both rare and common disorders. In its latest earnings report for the second quarter of 2025, Wave Life Sciences highlighted significant progress in its clinical trials, particularly in the RestorAATion-2 study for alpha-1 antitrypsin deficiency (AATD) and the INLIGHT trial for obesity.
The company reported that the RestorAATion-2 study of WVE-006, designed to address AATD-related lung and liver disease, is advancing well with data from the 200 mg cohort expected in the third quarter of 2025 and the 400 mg cohort in the fall of 2025. Additionally, the INLIGHT trial for WVE-007, targeting obesity, has shown promising results with expanded dosing in Cohort 2 due to favorable safety and efficacy data, with results anticipated by the end of 2025.
Financially, Wave Life Sciences reported a decrease in revenue to $8.7 million for the second quarter of 2025, compared to $19.7 million in the same period the previous year. The company experienced a net loss of $50.5 million, up from $32.9 million in the prior year quarter, attributed to increased research and development expenses. Despite this, the company maintains a strong cash position with $208.5 million in cash and cash equivalents, expected to fund operations into 2027.
Looking ahead, Wave Life Sciences remains optimistic about its pipeline, with plans to share multiple data sets in the latter half of 2025. The company is also preparing for significant regulatory milestones in 2026, including a potential New Drug Application for its Duchenne muscular dystrophy program. Wave’s management continues to emphasize the potential of its RNA medicines platform to deliver transformative treatments across various therapeutic areas.