Tango Therapeutics, Inc. ( (TNGX) ) has released its Q2 earnings. Here is a breakdown of the information Tango Therapeutics, Inc. presented to its investors.
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Tango Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing precision cancer medicines through the genetic principle of synthetic lethality. The company recently reported its financial results for the second quarter of 2025, highlighting significant progress in its clinical trials and strategic collaborations.
In the second quarter, Tango Therapeutics dosed the first patient in a combination trial of TNG462 with Revolution Medicines’ RAS(ON) inhibitors and initiated a Phase 1/2 trial with TNG456 for glioblastoma. The company also announced a mutual agreement with Gilead to shorten their collaboration term, which will result in recognizing $53.8 million in deferred revenue in the third quarter.
Financially, Tango reported a decrease in collaboration revenue to $3.2 million compared to $7.8 million in the same quarter of 2024, attributed to lower research costs. The company experienced a net loss of $38.9 million for the quarter, an increase from the previous year’s $25.6 million, primarily due to increased spending on advancing its pipeline.
Looking ahead, Tango Therapeutics plans to present clinical data for TNG462 and TNG260 in the second half of 2025. The company remains optimistic about its cash position, with $180.8 million in reserves expected to fund operations into early 2027, as it continues to advance its promising cancer therapies.

