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Silence Therapeutics’ Zerlasiran Shows Promising Results

Silence Therapeutics’ Zerlasiran Shows Promising Results

Silence Therapeutics (SLN) has released an update.

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Silence Therapeutics reports a breakthrough as its phase 2 study of zerlasiran shows substantial and sustained reductions in Lp(a), a key cardiovascular disease risk factor, paving the way for phase 3 trials. The medication, which uses siRNA technology to lower Lp(a) levels, was well received by patients and demonstrated a median reduction of approximately 90% without serious safety concerns. This development offers hope for addressing a significant unmet medical need in cardiovascular health.

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