Septerna, Inc. ( (SEPN) ) has released its Q2 earnings. Here is a breakdown of the information Septerna, Inc. presented to its investors.
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Septerna, Inc. is a biotechnology company specializing in G protein-coupled receptor (GPCR) drug discovery, focusing on developing innovative oral small molecule therapies for various therapeutic areas including endocrinology, immunology, inflammation, and metabolic diseases.
In its recent earnings report, Septerna highlighted significant business progress and financial results for the second quarter of 2025. The company is advancing its pipeline with key programs such as the PTH1R agonist for hypoparathyroidism and SEP-631 for mast cell diseases, alongside a strategic collaboration with Novo Nordisk.
Key financial metrics from the report include a cash position of $379.2 million as of June 30, 2025, bolstered by a $195 million upfront payment from Novo Nordisk. Research and development expenses increased to $22.2 million, while general and administrative expenses rose to $6.9 million, resulting in a net loss of $24.8 million for the quarter. The company is also progressing with its TSHR NAM program and other discovery-stage initiatives.
Looking ahead, Septerna is poised to continue its clinical advancements, with plans to initiate a Phase 1 trial for its PTH1R agonist in 2026 and ongoing development of its SEP-631 program. The collaboration with Novo Nordisk is expected to further enhance its research and development capabilities, supporting its goal of delivering impactful therapies.
With a strong financial position and a promising pipeline, Septerna remains focused on achieving its strategic milestones and advancing its innovative drug discovery efforts.