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Sanofi’s Promising Phase 2a Diabetes Study: A Potential Game-Changer?

Sanofi’s Promising Phase 2a Diabetes Study: A Potential Game-Changer?

Sanofi SA ((SNY)), Sanofi ((DE:SNW)), Sanofi ((SNYNF)) announced an update on their ongoing clinical study.

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Sanofi has launched a Phase 2a clinical study titled A 52-week Randomized, Double-blind, Placebo-controlled, Multi-center Phase 2a Study Assessing Safety and Efficacy of SAR442970, a Dual Anti-TNF-α and Anti-OX40L NANOBODY® Molecule, for Preservation of Pancreatic β-cell Function in Adults and Adolescents With Recently Diagnosed Type 1 Diabetes. The study aims to evaluate the safety and efficacy of SAR442970 in preserving pancreatic β-cell function in individuals with newly diagnosed type 1 diabetes.

The intervention being tested is SAR442970, a dual-action nanobody molecule targeting TNF-α and OX40L, administered via subcutaneous injection. Its purpose is to maintain pancreatic function in patients with type 1 diabetes.

This interventional study is randomized and employs a parallel assignment model with quadruple masking, involving participants, care providers, investigators, and outcomes assessors. The primary goal is treatment-focused, with a 3:1 randomization ratio between the active drug and placebo groups.

The study began on February 28, 2025, with a primary completion date set for 2026. The estimated study completion is expected later in 2026, with the latest update provided on August 21, 2025.

This study update could positively influence Sanofi’s stock performance by showcasing its commitment to innovative diabetes treatments. The progress may also affect investor sentiment, especially in comparison to competitors in the diabetes treatment market.

The study is currently recruiting, with further details available on the ClinicalTrials portal.

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