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PYC Therapeutics Advances RNA Drug Pipeline With Key Q4 2025 Clinical Milestones

Story Highlights
  • PYC advanced all four RNA therapeutic programs, with three in human trials and key safety and efficacy milestones achieved or initiated.
  • Clinical and preclinical progress in PKD, ADOA, RP11, and PMS strengthens PYC’s position in high-unmet-need genetic disease markets.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
PYC Therapeutics Advances RNA Drug Pipeline With Key Q4 2025 Clinical Milestones

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PYC Therapeutics Limited ( (AU:PYC) ) has provided an announcement.

In its fourth-quarter 2025 update, PYC Therapeutics reported continued progress across all four of its pipeline programs, highlighting key clinical milestones and positioning the company for important safety and efficacy read-outs over the next two years. The company established a favourable safety and tolerability profile for its polycystic kidney disease candidate in healthy volunteers, clearing the way for progression to patient studies; advanced its autosomal dominant optic atrophy program into a global repeat-dose trial aimed at demonstrating clinical proof of concept; presented longer-term data showing sustained vision improvement in patients with retinitis pigmentosa type 11 treated with its investigational therapy; and showcased preclinical data, including non-human primate results, to support moving its Phelan-McDermid syndrome candidate into clinical trials. Collectively, these developments underscore PYC’s execution against its clinical roadmap and strengthen its positioning as an emerging player in RNA therapeutics for high-unmet-need genetic diseases.

The most recent analyst rating on (AU:PYC) stock is a Hold with a A$1.50 price target. To see the full list of analyst forecasts on PYC Therapeutics Limited stock, see the AU:PYC Stock Forecast page.

More about PYC Therapeutics Limited

PYC Therapeutics Limited is a precision medicine biotechnology company developing RNA-based therapeutics for patients with severe genetic diseases that currently have no treatment options. The company is advancing a pipeline of four first-in-class drug candidates, three of which are already in human trials, targeting indications where RNA therapeutics can directly address underlying genetic causes, including diseases driven by haploinsufficiency.

Average Trading Volume: 470,837

Technical Sentiment Signal: Buy

Current Market Cap: A$979.9M

Find detailed analytics on PYC stock on TipRanks’ Stock Analysis page.

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