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The latest update is out from PainReform ( (PRFX) ).
On January 12, 2026, PainReform and its majority-owned subsidiary LayerBio reported that their OcuRing™-K drop-less, sustained-release intraocular drug delivery platform for cataract surgery demonstrated a favorable safety profile in a series of preclinical rabbit studies and a Phase I human clinical trial. The studies found no treatment-related adverse events, no serious adverse events, proper positioning of the investigational product and intraocular lenses in all treated eyes, and no meaningful safety differences versus controls, reinforcing the platform’s tolerability and biocompatibility and supporting advancement toward investigational new drug-enabling activities and later-stage clinical development in the United States, a step that could strengthen PainReform’s positioning in ophthalmic drug delivery and post-surgical care.
The most recent analyst rating on (PRFX) stock is a Hold with a $0.70 price target. To see the full list of analyst forecasts on PainReform stock, see the PRFX Stock Forecast page.
Spark’s Take on PRFX Stock
According to Spark, TipRanks’ AI Analyst, PRFX is a Neutral.
The score is driven primarily by very weak financial performance (minimal revenue, widening losses, and worsening cash burn with a shrinking equity cushion). Technicals also weigh on the score due to a clear downtrend versus key moving averages, partially offset by oversold indicators. Valuation contributes little support given negative earnings and no dividend yield.
To see Spark’s full report on PRFX stock, click here.
More about PainReform
PainReform Ltd. is a Tel Aviv-based, clinical-stage specialty pharmaceutical company that reformulates established therapeutics for post-operative pain management using sustained-release drug-delivery technologies, while also operating DeepSolar, an AI-driven energy analytics platform for optimizing solar asset performance across their lifecycle.
Average Trading Volume: 319,068
Technical Sentiment Signal: Strong Sell
Current Market Cap: $3.33M
For detailed information about PRFX stock, go to TipRanks’ Stock Analysis page.