Pacific Biosciences ( (PACB) ) has released its Q3 earnings. Here is a breakdown of the information Pacific Biosciences presented to its investors.
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Pacific Biosciences (PacBio) is a leading life science technology company specializing in advanced sequencing solutions aimed at addressing genetically complex problems across various research applications, including human germline sequencing and oncology.
In its third-quarter 2025 earnings report, PacBio revealed a slight decline in total revenue compared to the previous year, with notable achievements in consumable revenue and strategic advancements in sequencing technology.
The company reported a total revenue of $38.4 million for Q3 2025, down from $40.0 million in Q3 2024. Instrument revenue decreased significantly, while consumable revenue reached a record high of $21.3 million. PacBio also unveiled the SPRQ-Nx sequencing chemistry, promising a 40% reduction in sequencing costs, and achieved regulatory approval for its Sequel II CNDx system in China.
Despite a net loss of $38.0 million, PacBio improved its gross profit and reduced operating expenses compared to the previous year. The company continues to focus on expanding its gross margins and reducing costs, reflecting its commitment to making long-read sequencing more accessible globally.
Looking ahead, PacBio’s management remains optimistic about its strategic initiatives and technological advancements, aiming to enhance its competitive position in the genomic sequencing market and broaden the accessibility of its high-accuracy long-read sequencing technology worldwide.

