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Oncopeptides’ Pepaxti Shows Strong Phase 2 Data in Myeloma Patients With Renal Impairment

Story Highlights
  • Oncopeptides’ Phase 2 BRIDGE study shows Pepaxti can be safely used in relapsed, refractory multiple myeloma patients with moderate-to-severe renal impairment.
  • A reduced 30 mg Pepaxti dose maintained strong efficacy and stable kidney function, supporting broader clinical use and bolstering Oncopeptides’ position in difficult-to-treat myeloma.
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Oncopeptides AB ( (SE:ONCO) ) has shared an update.

Oncopeptides has reported Phase 2 BRIDGE study results showing that its cancer drug Pepaxti, combined with dexamethasone, can be safely and effectively used in relapsed, refractory multiple myeloma patients with moderate-to-severe renal impairment, a group that represents about half of all myeloma cases and typically has poorer outcomes. The peer-reviewed data demonstrate that a reduced 30 mg starting dose in patients with moderate renal impairment maintains a manageable safety profile, robust response rates, and stable or slightly improved kidney function, thereby supporting wider clinical use of Pepaxti in fragile patient populations and strengthening the company’s scientific position in this indication.

More about Oncopeptides AB

Oncopeptides AB is a Swedish biotech company specializing in targeted therapies for difficult-to-treat cancers, leveraging its proprietary Peptide Drug Conjugate and SPiKE platforms to deliver cytotoxic agents directly into cancer cells. Its flagship drug Pepaxti is being commercialized in Europe, supported by partnership agreements in South Korea, the Middle East, Africa and other regions, with operations across several European countries and a listing on Nasdaq Stockholm.

Average Trading Volume: 4,737,545

Technical Sentiment Signal: Sell

Current Market Cap: SEK664M

For detailed information about ONCO stock, go to TipRanks’ Stock Analysis page.

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