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Ocugen Reports Encouraging 12-Month Data for OCU410

Story Highlights
  • Ocugen reported strong 12-month Phase 1 and 2 data for OCU410 gene therapy in geographic atrophy.
  • OCU410 showed significant lesion and retinal degeneration reductions with no serious safety issues, strengthening its competitive outlook as a potential one-time treatment.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Ocugen Reports Encouraging 12-Month Data for OCU410

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Ocugen ( (OCGN) ) has shared an update.

On January 15, 2026, Ocugen reported positive preliminary 12‑month data from its Phase 1 and Phase 2 ArMaDa trials of OCU410, an AAV5-based modifier gene therapy for geographic atrophy secondary to dry age-related macular degeneration, a condition affecting millions worldwide and poorly served by existing treatments. In the Phase 2 trial, about half of enrolled patients evaluated at 12 months showed a 46% reduction in lesion growth versus control across medium and high doses, with the medium dose alone achieving a 54% reduction and no OCU410-related serious adverse events observed, while Phase 1 data indicated 60% slower ellipsoid zone loss and preservation of photoreceptors and retinal pigment epithelium, underscoring a potentially favorable risk-benefit profile and positioning OCU410 as a prospective one-time alternative to chronic injection-based therapies as Ocugen advances toward later-stage development and eventual regulatory filings.

The most recent analyst rating on (OCGN) stock is a Hold with a $2.00 price target. To see the full list of analyst forecasts on Ocugen stock, see the OCGN Stock Forecast page.

Spark’s Take on OCGN Stock

According to Spark, TipRanks’ AI Analyst, OCGN is a Neutral.

Score is held back primarily by weak financial performance (ongoing losses, very high leverage, and challenged cash flow). Offsetting factors include a strong technical uptrend with positive MACD (though momentum is overbought) and an earnings call that emphasized meaningful clinical/program progress and extended runway, while valuation remains difficult to support due to negative earnings and no dividend.

To see Spark’s full report on OCGN stock, click here.

More about Ocugen

Ocugen, Inc. is a biotechnology company specializing in the discovery, development, and commercialization of novel gene therapies for major blindness diseases, leveraging a gene-agnostic modifier gene therapy platform aimed at large patient populations with significant unmet medical need in conditions such as dry age-related macular degeneration and geographic atrophy.

Average Trading Volume: 3,949,177

Technical Sentiment Signal: Buy

Current Market Cap: $587.2M

For detailed information about OCGN stock, go to TipRanks’ Stock Analysis page.

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