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Nexalis Screens First Patient in Phase 2 IRX-211 Trial for Breakthrough Cancer Pain

Story Highlights
  • Nexalis has begun a Phase 2 trial of inhaled IRX-211 for breakthrough cancer pain, enrolling 156 opioid-tolerant patients.
  • The study targets unmet need in fast-onset cancer pain and could support Nexalis’s clinical value and partnering prospects.
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Nexalis Screens First Patient in Phase 2 IRX-211 Trial for Breakthrough Cancer Pain

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InhaleRx Limited ( (AU:NX1) ) has shared an announcement.

Nexalis Therapeutics has reached a key development milestone with the first patient screened in its Phase 2 trial of IRX-211 for breakthrough cancer pain, moving the program into controlled clinical evaluation in its intended patient population. The multicentre, randomised, double-blind, placebo-controlled cross-over study will enrol about 156 opioid-tolerant cancer patients, using an initial open-label titration phase to individualise dosing before a cross-over comparison of IRX-211 against placebo.

The trial is designed to assess efficacy, safety and patient-reported outcomes in a condition where existing opioid therapies often fail to provide sufficiently rapid relief, and where market demand is expected to expand significantly over the next decade. Successful results would not only validate IRX-211’s fast-acting inhaled approach for poorly controlled breakthrough cancer pain but also position Nexalis for value-driving clinical data and potential future partnering opportunities in the global cancer pain market.

More about InhaleRx Limited

Nexalis Therapeutics Ltd is an Australian clinical-stage biopharmaceutical company focused on oncology supportive care. Its lead candidate, IRX-211, is a proprietary inhaled therapy being developed to provide rapid, predictable and patient-controlled relief for breakthrough cancer pain in opioid-tolerant cancer patients, targeting a large and growing global cancer pain market.

Average Trading Volume: 214,969

Technical Sentiment Signal: Sell

Current Market Cap: A$4.81M

For detailed information about NX1 stock, go to TipRanks’ Stock Analysis page.

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