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NervGen Maps Path to Phase 3 as NVG-291 Data Strengthen Neuroreparative Ambitions

Story Highlights
  • NervGen reported strong 2025 progress, with NVG-291 showing significant and durable functional gains in chronic tetraplegia patients in the CONNECT SCI study.
  • Following an End-of-Phase 2 FDA meeting, NervGen plans a mid-2026 Phase 3 trial and broader NVG-291 indication expansion, supported by Nasdaq listing and regulatory flexibility.
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NervGen Maps Path to Phase 3 as NVG-291 Data Strengthen Neuroreparative Ambitions

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An update from NervGen Pharma ( (NGEN) ) is now available.

NervGen Pharma reported its full-year 2025 results and outlined progress on its NVG-291 program, highlighting positive Phase 1b/2a CONNECT SCI data in chronic tetraplegia that showed statistically significant improvements in corticospinal connectivity and functional hand use, with durable benefits beyond the treatment period. The company has completed an End-of-Phase 2 meeting with the FDA and, supported by multiple potential regulatory pathways and a recent Nasdaq listing, plans to initiate a Phase 3 trial in mid-2026, present further biomechanical gait data, and prioritize expansion of NVG-291 into additional neurotraumatic and neurologic indications, reinforcing its ambition to emerge as a leader in neuroreparative therapeutics.

The most recent analyst rating on (NGEN) stock is a Buy with a $6.75 price target. To see the full list of analyst forecasts on NervGen Pharma stock, see the NGEN Stock Forecast page.

More about NervGen Pharma

NervGen Pharma is a clinical-stage biopharmaceutical company focused on developing first-in-class neuroreparative therapeutics for spinal cord injury and other neurotraumatic and neurologic conditions. The company is advancing its lead candidate NVG-291, targeting chronic and subacute tetraplegia, and aims to expand into additional indications based on extensive preclinical efficacy data.

Average Trading Volume: 139,305

Technical Sentiment Signal: Buy

Current Market Cap: $294.4M

For an in-depth examination of NGEN stock, go to TipRanks’ Overview page.

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