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MetaVia Announces Positive Phase 2a Trial Results

Story Highlights
  • MetaVia Inc. announced positive Phase 2a trial results for vanoglipel as a MASH treatment.
  • Vanoglipel showed improvements in glucose control, liver health, and plasma lipidomic profiles.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
MetaVia Announces Positive Phase 2a Trial Results

Meet Your ETF AI Analyst

The latest announcement is out from MetaVia ( (MTVA) ).

On November 7, 2025, MetaVia Inc. announced positive results from its Phase 2a clinical trial of vanoglipel (DA-1241), a GPR119 agonist, as a potential treatment for MASH. The trial demonstrated vanoglipel’s ability to improve glucose control, liver health, and plasma lipidomic profiles after 16 weeks of treatment, highlighting its potential to address both hepatic and metabolic components of MASH. The data, presented at the AASLD The Liver Meeting® 2025, showed significant reductions in HbA1c, liver inflammation, and fibrosis, reinforcing vanoglipel’s potential as a monotherapy and combination therapy for MASH and related metabolic disorders.

The most recent analyst rating on (MTVA) stock is a Buy with a $12.00 price target. To see the full list of analyst forecasts on MetaVia stock, see the MTVA Stock Forecast page.

Spark’s Take on MTVA Stock

According to Spark, TipRanks’ AI Analyst, MTVA is a Underperform.

MetaVia’s overall stock score is heavily impacted by its poor financial performance, characterized by persistent losses and no revenue generation. The technical analysis indicates weak market momentum, and negative valuation metrics highlight the stock’s high-risk profile. Although recent positive trial results provide some potential for future growth, significant strategic changes are necessary for the company to achieve financial stability and investor confidence.

To see Spark’s full report on MTVA stock, click here.

More about MetaVia

MetaVia Inc. is a clinical-stage biotechnology company focused on transforming cardiometabolic diseases. The company is currently developing DA-1726 for obesity treatment and Vanoglipel (DA-1241) for Metabolic Dysfunction-Associated Steatohepatitis (MASH).

Average Trading Volume: 1,954,059

Technical Sentiment Signal: Sell

Current Market Cap: $24.2M

Learn more about MTVA stock on TipRanks’ Stock Analysis page.

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