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Kalaris Therapeutics Reports Q3 2025 Financial Progress

Kalaris Therapeutics Reports Q3 2025 Financial Progress

Kalaris Therapeutics, Inc. ( (KLRS) ) has released its Q3 earnings. Here is a breakdown of the information Kalaris Therapeutics, Inc. presented to its investors.

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Kalaris Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing treatments for retinal diseases, including neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO). Founded by Dr. Napoleone Ferrara, the company aims to advance novel therapeutic approaches for sight-threatening conditions.

In its latest earnings report, Kalaris Therapeutics announced significant progress in its clinical trials and corporate developments. The company is on track to report initial clinical data from its Phase 1a trial by the end of 2025 and has begun enrolling patients for its Phase 1b/2 trial. Additionally, Kalaris has strengthened its corporate structure by selecting a Contract Development and Manufacturing Organization (CDMO) and hiring a new Chief Financial Officer.

Key financial highlights include a substantial increase in cash reserves to $77 million, expected to fund operations into 2027. The company reported a decrease in research and development expenses due to a previous royalty obligation, while general and administrative expenses rose due to increased operational costs as a public company. Kalaris reported a net loss of $11.9 million for the third quarter of 2025, a significant improvement from the $38.1 million loss in the same period last year.

Looking ahead, Kalaris Therapeutics remains focused on advancing its clinical development program for TH103, a dual-targeting biologic designed to treat retinal diseases. With ongoing trials and strategic corporate developments, the company is poised to make significant strides in the biopharmaceutical sector, aiming to address unmet medical needs in retinal disease treatment.

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