Io Biotech, Inc. ( (IOBT) ) has released its Q2 earnings. Here is a breakdown of the information Io Biotech, Inc. presented to its investors.
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IO Biotech, Inc. is a clinical-stage biopharmaceutical company focused on developing novel, immune-modulatory, off-the-shelf therapeutic cancer vaccines, with its primary operations in the biopharmaceutical sector. The company is advancing its lead cancer vaccine candidate, Cylembio, through clinical trials.
In its second quarter of 2025 earnings report, IO Biotech highlighted significant progress in its clinical trials, particularly the Phase 3 trial of Cylembio in combination with KEYTRUDA for advanced melanoma. Although the trial showed clinical improvement in progression-free survival, it narrowly missed statistical significance, prompting plans for discussions with the FDA.
Key financial metrics from the report include a net loss of $26.2 million for the quarter, an increase from the previous year’s $20.7 million. Research and development expenses rose slightly to $16.7 million, while general and administrative expenses increased to $6.5 million. The company’s cash position at the end of the quarter was $28.1 million, with additional funding expected to sustain operations into early 2026.
Strategically, IO Biotech plans to present at upcoming investor conferences and anticipates releasing further data from ongoing Phase 2 trials in the latter half of 2025. The company is also preparing for potential regulatory submissions based on its trial results.
Looking ahead, IO Biotech remains focused on advancing its pipeline and engaging with regulatory bodies to explore the potential for Cylembio’s approval, while managing its financial resources to support ongoing operations and future developments.

