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Henlius Wins Australian Nod for First-in-Class Bispecific Cancer ADC Trial

Story Highlights
  • Henlius secured Australian approval for a phase 1 trial of HLX48, a bispecific ADC targeting EGFR and c-MET in advanced solid tumors.
  • If successfully developed, HLX48 could become the first globally marketed bispecific ADC against EGFR and c-MET, though clinical and commercial outcomes remain uncertain.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Henlius Wins Australian Nod for First-in-Class Bispecific Cancer ADC Trial

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Shanghai Henlius Biotech, Inc. Class H ( (HK:2696) ) has issued an update.

Shanghai Henlius Biotech has obtained Australian approval to begin a phase 1 clinical trial for HLX48, a bispecific antibody-drug conjugate targeting EGFR and c-MET for advanced or metastatic solid tumors. The therapy is designed to combine targeted cytotoxic payload delivery with immune-mediated mechanisms to inhibit tumor growth while aiming for a favorable safety profile.

Preclinical data suggest HLX48 offers promising anti-tumor efficacy, and it would be the first bispecific ADC against both EGFR and c-MET if successfully commercialized globally. The company, however, cautions investors that successful development and commercialization are not guaranteed, underscoring both the opportunity and clinical risk inherent in this early-stage asset.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$99.78 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

More about Shanghai Henlius Biotech, Inc. Class H

Shanghai Henlius Biotech, Inc. is a China-based biopharmaceutical company specializing in the independent development of innovative biologic drugs, including antibody-based therapies. Listed in Hong Kong, the company focuses on oncology and other serious diseases, targeting global markets through both in-house R&D and international clinical development.

Average Trading Volume: 934,733

Technical Sentiment Signal: Buy

Current Market Cap: HK$39.13B

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